Concepedia

Liver X receptor inverse agonist SR9243 attenuates rheumatoid arthritis via modulating glycolytic metabolism of macrophages

De-Chong Zheng, Jia-Qin Hu, Chu-Tian Mai, Li Huang, Hua Zhou, Lili Yu, Ying Xie

Acta Pharmacologica Sinica · 2024 · 19 citations · 25 references

DOIFull text

Open access

Concepts

References

25

mTOR- and HIF-1α–mediated aerobic glycolysis as metabolic basis for trained immunity

Shih‐Chin Cheng, Jessica Quintin, Robert A. Cramer et al. · Science · 2014 · 2.1K citations

, , +17

Defining inflammatory cell states in rheumatoid arthritis joint synovial tissues by integrating single-cell transcriptomics and mass cytometry

Fan Zhang, Kevin Wei, Kamil Slowikowski et al. · Nature Immunology · 2019 · 1.4K citations · Full text

, , +15

AMPK Is a Negative Regulator of the Warburg Effect and Suppresses Tumor Growth In Vivo

Brandon Faubert, Gino Boily, Said Izreig et al. · Cell Metabolism · 2012 · 911 citations · Full text

, , +17

The TSC-mTOR pathway regulates macrophage polarization

Vanessa Byles, Anthony J. Covarrubias, Issam Ben‐Sahra et al. · Nature Communications · 2013 · 627 citations · Full text

, , +9

Broad Anti-tumor Activity of a Small Molecule that Selectively Targets the Warburg Effect and Lipogenesis

Colin A. Flaveny, Kristine Griffett, Melissa Kazantzis et al. · Cancer Cell · 2015 · 212 citations · Full text

, , +16