Concepedia

Broad Anti-tumor Activity of a Small Molecule that Selectively Targets the Warburg Effect and Lipogenesis

Colin A. Flaveny, Kristine Griffett, Melissa Kazantzis, Monideepa Sengupta, Antonio L. Amelio, Arindam Chatterjee, John K. Walker, Laura A. Solt, Theodore M. Kamenecka, Thomas P. Burris

Cancer Cell · 2015 · 212 citations · 41 references

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41

THE METABOLISM OF TUMORS IN THE BODY

Otto Warbürg, Franz Wind, Erwin Negelein · The Journal of General Physiology · 1927 · 4.4K citations · Full text

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Direct and Indirect Mechanisms for Regulation of Fatty Acid Synthase Gene Expression by Liver X Receptors

Sean B. Joseph, Bryan Laffitte, Parthive H. Patel et al. · Journal of Biological Chemistry · 2002 · 764 citations · Full text

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Ketones and lactate “fuel” tumor growth and metastasis

Gloria Bonuccelli, Aristotelis Tsirigos, Diana Whitaker‐Menezes et al. · Cell Cycle · 2010 · 569 citations

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Activation of liver X receptor improves glucose tolerance through coordinate regulation of glucose metabolism in liver and adipose tissue

Bryan Laffitte, Lily C. Chao, Jing Li et al. · Proceedings of the National Academy of Sciences · 2003 · 495 citations

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Stimulation of Lipogenesis by Pharmacological Activation of the Liver X Receptor Leads to Production of Large, Triglyceride-rich Very Low Density Lipoprotein Particles

Aldo Grefhorst, Baukje M. Elzinga, Peter J. Voshol et al. · Journal of Biological Chemistry · 2002 · 493 citations · Full text

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