Concepedia

Ursolic acid inhibits NF-κB signaling and attenuates MMP-9/TIMP-1 in progressive osteoarthritis: a network pharmacology-based analysis

Eman Maher Zahran, Soad A. Mohamad, Mohamed M. Elsayed, Mohamed Hisham, Sherif A. Maher, Usama Ramadan Abdelmohsen, Mahmoud A. Elrehany, Samar Yehia Desoukey, Mohamed Salah Kamel

RSC Advances · 2024 · 15 citations · 43 references

DOIFull text

Open access

Concepts

Abstract

Osteoarthritis (OA) is a degenerative joint disease, characterized by infiltration of monocytes into the synovial joint which promotes inflammation, stiffness, joint swelling, cartilage degradation and further bone destruction.

References

43

Cytoscape: A Software Environment for Integrated Models of Biomolecular Interaction Networks

Paul Shannon, Andrew Markiel, Owen Ozier et al. · Genome Research · 2003 · 54.3K citations · Full text

, , +17

TCMSP: a database of systems pharmacology for drug discovery from herbal medicines

Jinlong Ru, Peng Li, Jinan Wang et al. · Journal of Cheminformatics · 2014 · 5K citations · Full text

, , +16

Guide for the Care and Use of Laboratory Animals (8th edn)

Udo Albus · Laboratory Animals · 2012 · 1.7K citations · Full text

, , +9

Methods Used to Evaluate Pain Behaviors in Rodents

Jennifer R. Deuis, Lucie Dvořáková, Irina Vetter · Frontiers in Molecular Neuroscience · 2017 · 1.3K citations · Full text

, , +12

Understanding ZHENG in traditional Chinese medicine in the context of neuro-endocrine-immune network

Shao Li, Zhi-Kang Zhang, Liji Wu et al. · IET Systems Biology · 2007 · 370 citations

, , +15