Concepedia

The dynamic process of mRNA delivery by lipid nanoparticles in vivo

Runpu Ma, Yuting Li, Yi Wei, Juanjuan Zhou, Jinya Ma, Mengke Zhang, Junyi Tu, Jinhong Jiang, Sitao Xie, Weihong Tan,

Nano Today · 2024 · 33 citations · 31 references

DOI

Concepts

References

31

The Onpattro story and the clinical translation of nanomedicines containing nucleic acid-based drugs

Akin Akinc, Martin A. Maier, Muthiah Manoharan et al. · Nature Nanotechnology · 2019 · 1.6K citations · Full text

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Expression kinetics of nucleoside-modified mRNA delivered in lipid nanoparticles to mice by various routes

Norbert Pardi, Steven Tuyishime, Hiromi Muramatsu et al. · Journal of Controlled Release · 2015 · 1K citations

, , +17

Optimization of Lipid Nanoparticles for Intramuscular Administration of mRNA Vaccines

Kimberly J. Hassett, Kerry E. Benenato, Eric Jacquinet et al. · Molecular Therapy — Nucleic Acids · 2019 · 888 citations · Full text

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A Novel Amino Lipid Series for mRNA Delivery: Improved Endosomal Escape and Sustained Pharmacology and Safety in Non-human Primates

Staci Sabnis, E. Sathyajith Kumarasinghe, Timothy Salerno et al. · Molecular Therapy · 2018 · 794 citations · Full text

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On the Formation and Morphology of Lipid Nanoparticles Containing Ionizable Cationic Lipids and siRNA

Jayesh A. Kulkarni, Maria M. Darjuan, Joanne E. Mercer et al. · ACS Nano · 2018 · 620 citations

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