Concepedia

The TLR4/NF-κB/NLRP3 and Nrf2/HO-1 pathways mediate the neuroprotective effects of alkaloids extracted from Uncaria rhynchophylla in Parkinson's disease

Chunxia Zhang, Jiayu Zhou, Lingxin Zhuo, Wenxin Zhang, Lingrui Lv, Lingmeng Zhu, Jia‐Yi Zhang, Feng Feng, Wenyuan Liu, Lingfei Han,

Journal of Ethnopharmacology · 2024 · 13 citations · 40 references

DOI

Concepts

References

40

Dopamine Controls Systemic Inflammation through Inhibition of NLRP3 Inflammasome

Yiqing Yan, Wei Jiang, Lei Liu et al. · Cell · 2015 · 1K citations · Full text

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Inflammasome inhibition prevents α-synuclein pathology and dopaminergic neurodegeneration in mice

Richard D. Gordon, Eduardo A. Albornoz, Daniel C. Christie et al. · Science Translational Medicine · 2018 · 890 citations

, , +17

Parkinson disease: from pathology to molecular disease mechanisms

David T. Dexter, Peter Jenner · Free Radical Biology and Medicine · 2013 · 709 citations

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Fecal microbiota transplantation protects rotenone-induced Parkinson’s disease mice via suppressing inflammation mediated by the lipopolysaccharide-TLR4 signaling pathway through the microbiota-gut-brain axis

Zhe Zhao, Jingwen Ning, Meiyu Shang et al. · Microbiome · 2021 · 576 citations · Full text

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Melatonin Attenuates LPS-Induced Acute Depressive-Like Behaviors and Microglial NLRP3 Inflammasome Activation Through the SIRT1/Nrf2 Pathway

Burak I. Ariöz, Bora Tastan, Emre Tarakcioglu et al. · Frontiers in Immunology · 2019 · 523 citations · Full text

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