Concepedia

Discovery of novel 1,2,4-triazole tethered β-hydroxy sulfides as bacterial tyrosinase inhibitors: synthesis and biophysical evaluation through <i>in vitro</i> and <i>in silico</i> approaches

Sadaf Saeed, Muhammad Jawwad Saif, Ameer Fawad Zahoor, Hina Tabassum, Shagufta Kamal, Shah Faisal, Rabia Ashraf, Samreen Gul Khan, Usman Nazeer, Ali Irfan,

RSC Advances · 2024 · 12 citations · 45 references

DOIFull text

Open access

Concepts

Abstract

anti-tyrosinase assay results; therefore, the molecule 11c can be the lead bacterial tyrosinase inhibitor as well as the antibacterial agent against both types of bacterial strains after suitable structural modifications.

References

45

AutoDock Vina: Improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading

Oleg Trott, Arthur J. Olson · Journal of Computational Chemistry · 2009 · 37.1K citations · Full text

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SWISS-MODEL: homology modelling of protein structures and complexes

Andrew Waterhouse, Martino Bertoni, Stefan Bienert et al. · Nucleic Acids Research · 2018 · 13.6K citations · Full text

, , +15

AutoDock Vina 1.2.0: New Docking Methods, Expanded Force Field, and Python Bindings

Jérôme Eberhardt, Diogo Santos‐Martins, Andreas F. Tillack et al. · Journal of Chemical Information and Modeling · 2021 · 6.7K citations · Full text

, , +15

Microtitre plate-based antibacterial assay incorporating resazurin as an indicator of cell growth, and its application in the in vitro antibacterial screening of phytochemicals

Satyajit D. Sarker, Lutfun Nahar, Yashodharan Kumarasamy · Methods · 2007 · 1.8K citations · Full text

, , +12

Quercetin as a tyrosinase inhibitor: Inhibitory activity, conformational change and mechanism

Meihui Fan, Guowen Zhang, Xing Hu et al. · Food Research International · 2017 · 255 citations

, , +8