Phytomedicine · 2024 · 24 citations · 42 references
JLD acted on TP53 to regulate the TNF and TGFβ1 signaling pathways, effectively alleviating cardiomyocyte hypertrophy and inflammation in high glucose and diabetic conditions. Our study provides a solid foundation for the future treatment of diabetic cardiomyopathy with JLD.
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Mdm2 promotes the rapid degradation of p53
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