Resolution of Acinar Dedifferentiation Regulates Tissue Remodeling in Pancreatic Injury and Cancer Initiation

Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse

Sunil R. Hingorani, Emanuel F. Petricoin, Anirban Maitra et al. · Cancer Cell · 2003 · 2.5K citations · Full text

Medicine, Oncology, Pathology +12

Oncogenic Kras Maintains Pancreatic Tumors through Regulation of Anabolic Glucose Metabolism

Haoqiang Ying, Alec C. Kimmelman, Costas A. Lyssiotis et al. · Cell · 2012 · 2K citations · Full text

Medicine, Cancer Biology, Oncology +11

Tuft-cell-derived IL-25 regulates an intestinal ILC2–epithelial response circuit

Jakob von Moltke, Ming Ji, Hong-Erh Liang et al. · Nature · 2015 · 1.2K citations · Full text

Life Sciences, Cell Biology, Immunology +12

Identification of Sox9-Dependent Acinar-to-Ductal Reprogramming as the Principal Mechanism for Initiation of Pancreatic Ductal Adenocarcinoma

Janel L. Kopp, Guido von Figura, Erin Mayes et al. · Cancer Cell · 2012 · 692 citations

Medicine, Molecular Biology, Molecular Genetics +13

KrasG12D-Induced IKK2/β/NF-κB Activation by IL-1α and p62 Feedforward Loops Is Required for Development of Pancreatic Ductal Adenocarcinoma

Jianhua Ling, Ya’an Kang, Ruiying Zhao et al. · Cancer Cell · 2012 · 520 citations

Life Sciences, Cell Biology, Oncology +11