Decreased HMGCS1 inhibits proliferation and inflammatory response of keratinocytes and ameliorates imiquimod-induced psoriasis via the STAT3/IL-23 axis

Stat3 links activated keratinocytes and immunocytes required for development of psoriasis in a novel transgenic mouse model

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IL-22 and IL-20 are key mediators of the epidermal alterations in psoriasis while IL-17 and IFN-γ are not

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Involvement of interleukin-21 in the epidermal hyperplasia of psoriasis

Roberta Caruso, Elisabetta Botti, Massimiliano Sarra et al. · Nature Medicine · 2009 · 199 citations · Full text

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IL-19 Is a Component of the Pathogenetic IL-23/IL-17 Cascade in Psoriasis

Ellen Witte, Georgios Kokolakis, Katrin Witte et al. · Journal of Investigative Dermatology · 2014 · 162 citations · Full text

Life Sciences, Dermatology, Immunology +12

Intestinal dysbiosis exacerbates the pathogenesis of psoriasis-like phenotype through changes in fatty acid metabolism

Qixiang Zhao, Jiadong Yu, Hong Zhou et al. · Signal Transduction and Targeted Therapy · 2023 · 116 citations · Full text

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