BEHAV3D: a 3D live imaging platform for comprehensive analysis of engineered T cell behavior and tumor response

Patient-derived organoids model treatment response of metastatic gastrointestinal cancers

Georgios Vlachogiannis, Somaieh Hedayat, Alexandra Vatsiou et al. · Science · 2018 · 2.1K citations · Full text

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Generation of Tumor-Reactive T Cells by Co-culture of Peripheral Blood Lymphocytes and Tumor Organoids

Krijn K. Dijkstra, Chiara M. Cattaneo, Fleur Weeber et al. · Cell · 2018 · 1.1K citations · Full text

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Cancer modeling meets human organoid technology

David A. Tuveson, Hans Clevers · Science · 2019 · 922 citations

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Culture and establishment of self-renewing human and mouse adult liver and pancreas 3D organoids and their genetic manipulation

Laura Broutier, Amanda Andersson-Rolf, Christopher J. Hindley et al. · Nature Protocols · 2016 · 879 citations · Full text

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Patient-derived organoids can predict response to chemotherapy in metastatic colorectal cancer patients

Salo Ooft, Fleur Weeber, Krijn K. Dijkstra et al. · Science Translational Medicine · 2019 · 826 citations

Medicine, Oncology, Pharmacology +17