On Antimicrobial Polymers: Development, Mechanism of Action, International Testing Procedures, and Applications

Abstract

The development of antimicrobial polymeric materials has evolved into one of the more promising methods for preventing the growth of microbes and mitigating the spread of infectious diseases in several applications including the health and food packaging sectors. The outbreak of global pandemics, and particularly the recent COVID-19 pandemic, further strengthen the importance of developing such solutions. This review paper presents a fundamental understanding of how antimicrobial polymers are developed, describes the possible surface modification approaches to render polymers with antimicrobial properties, highlights the potential mechanism of action against a range of microorganisms (bacterial, viral, and fungal), and details some of the international standard protocols and procedures to evaluate the antimicrobial properties of modified materials (such as plastics and textiles). In addition, this review paper discusses the toxicity of antimicrobial additives when used in healthcare and food packaging applications.