Vesicles and Liposomes: A Self‐Assembly Principle Beyond Lipids

TLDR

Vesicle and liposome research has expanded beyond lipids, with polymer self‑assembly forming closed hull structures that enable new materials science applications. The report outlines potential applications of vesicles, including non‑lipid vesicles. The authors review new polymer and supramolecular tectons that generalize vesicle formation beyond lipids.

Abstract

Abstract This Progress Report describes the latest advances in vesicles and liposomes. Recent work on the self‐assembly of complex polymer systems shows that the formation of polymer vesicles or closed hull structures is archetypal, leading to fascinating new possibilities and applications in materials science. A general view of the underlying self‐assembly mechanisms leading to vesicles and the control of size, shape, and other vesicular properties by physicochemical means is presented, as background. This is followed by an overview of the recently described new classes of polymer and supramolecular tectons that make vesicle formation a more general phenomenon going beyond just lipids. Finally, the potential applications of vesicles, including non‐lipid vesicles, are outlined.