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Publication | Open Access

Cytidine Deaminase Resolves Replicative Stress and Protects Pancreatic Cancer from DNA-Targeting Drugs

DOIFull Paper Access

12

Citations

45

References

2024

Year

Audrey Lumeau, Nicolas Béry, Audrey Francès, Marion Gayral, Guillaume Labrousse, Cyril Ribeyre, Charlene Lopez, Adèle Nevot, Abdessamad El Kaoutari, Naı̈ma Hanoun,
Cancer Research

Abstract

Cytidine deaminase reduces replication stress and regulates DNA replication to confer resistance to DNA-damaging drugs in pancreatic cancer, unveiling a molecular vulnerability that could enhance treatment response.

References

YearCitations

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