Concepedia

MicroRNA-21's role in PTEN suppression and PI3K/AKT activation: Implications for cancer biology

Himmat Singh Chawra, Mohit Agarwal, Anurag Mishra, Ravindra Pal Singh, Mithilesh Singh

Pathology - Research and Practice · 2024 · 74 citations · 99 references

DOI

Concepts

References

99

Targeting PI3K/Akt/mTOR Signaling in Cancer

Camillo Porta, Chiara Paglino, Alessandra Mosca · Frontiers in Oncology · 2014 · 1.5K citations · Full text

, , +15

Programmed Cell Death 4 (PDCD4) Is an Important Functional Target of the MicroRNA miR-21 in Breast Cancer Cells

Lisa B. Frankel, Nanna R. Christoffersen, Morten Lindow et al. · Journal of Biological Chemistry · 2007 · 1.1K citations · Full text

, , +17

Essential Role for Nuclear PTEN in Maintaining Chromosomal Integrity

Wen Shen, Adayabalam S. Balajee, Jianli Wang et al. · Cell · 2007 · 965 citations

, , +12

MicroRNA-21 Targets a Network of Key Tumor-Suppressive Pathways in Glioblastoma Cells

Thales Papagiannakopoulos, Alice Shapiro, Kenneth S. Kosik · Cancer Research · 2008 · 704 citations · Full text

, , +17

The PI3K/AKT/mTOR interactive pathway

Tülin Erşahin, Nurcan Tunçbağ, Rengül Çetin-Atalay · Molecular BioSystems · 2015 · 680 citations · Full text

, , +17