Bridging neurotrophic factors and bioactive peptides to Alzheimer's disease

A role for mitochondria in NLRP3 inflammasome activation

Rongbin Zhou, Amir S. Yazdi, Philippe Menu et al. · Nature · 2010 · 5.4K citations

Life Sciences, Cell Biology, Molecular Biology +12

A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis

Pontus Boström, Jun Wu, Mark P. Jedrychowski et al. · Nature · 2012 · 4.7K citations · Full text

Life Sciences, Genetics, Molecular Biology +16

Adult hippocampal neurogenesis is abundant in neurologically healthy subjects and drops sharply in patients with Alzheimer’s disease

Elena P. Moreno‐Jiménez, Miguel Flor‐García, Julia Terreros‐Roncal et al. · Nature Medicine · 2019 · 1.6K citations

Life Sciences, Neurobiology, Neuroscience +15

Exercise-linked FNDC5/irisin rescues synaptic plasticity and memory defects in Alzheimer’s models

Mychael V. Lourenco, Rudimar Luiz Frozza, Guilherme B. de Freitas et al. · Nature Medicine · 2018 · 931 citations · Full text

Life Sciences, Neurobiology, Neuroscience +16

Combined adult neurogenesis and BDNF mimic exercise effects on cognition in an Alzheimer’s mouse model

Se Hoon Choi, Enjana Bylykbashi, Zena K. Chatila et al. · Science · 2018 · 820 citations · Full text

Medicine, Neurobiology, Neuroscience +17