Prodrugs: Harnessing chemical modifications for improved therapeutics

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Medicine, Cardiology, Pharmacotherapy +12

T2Rs Function as Bitter Taste Receptors

Jayaram Chandrashekar, Ken L. Mueller, Mark A. Hoon et al. · Cell · 2000 · 1.4K citations · Full text

Life Sciences, Pharmacology, Physiology +13

A Comparison of Physiochemical Property Profiles of Development and Marketed Oral Drugs

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Nonpeptide angiotensin II receptor antagonists: the discovery of a series of N-(biphenylylmethyl)imidazoles as potent, orally active antihypertensives

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Pharmacy, Medicinal Chemistry, Pharmacology +13

Blood-Brain Barrier: Penetration of Morphine, Codeine, Heroin, and Methadone after Carotid Injection

William H. Oldendorf, Susan Hyman, Leon D. Braun et al. · Science · 1972 · 361 citations

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