Angiotensin II type-2 receptor attenuates liver fibrosis progression by suppressing IRE1α-XBP1 pathway

XBP1 mRNA Is Induced by ATF6 and Spliced by IRE1 in Response to ER Stress to Produce a Highly Active Transcription Factor

Hiderou Yoshida, Toshie Matsui, Akira Yamamoto et al. · Cell · 2001 · 4.1K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +13

XBP1 Controls Diverse Cell Type- and Condition-Specific Transcriptional Regulatory Networks

Diego Acosta‐Alvear, Yiming Zhou, Alexandre Blais et al. · Molecular Cell · 2007 · 857 citations · Full text

Life Sciences, Molecular Biology, Molecular Genetics +14

Angiotensin-II type 1 receptor interaction is a major regulator for liver fibrosis development in rats

Hitoshi Yoshiji, Shigeki Kuriyama, Junichi Yoshii et al. · Hepatology · 2001 · 383 citations

Medicine, Pharmacology, Pharmacotherapy +16

FXR Inhibits Endoplasmic Reticulum Stress-Induced NLRP3 Inflammasome in Hepatocytes and Ameliorates Liver Injury

Chang Yeob Han, Hyun Soo Rho, Ayoung Kim et al. · Cell Reports · 2018 · 228 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Endoplasmic Reticulum Stress in Hepatic Stellate Cells Promotes Liver Fibrosis via PERK-Mediated Degradation of HNRNPA1 and Up-regulation of SMAD2

Ja Hyun Koo, Hyo Ju Lee, Won Kim et al. · Gastroenterology · 2015 · 222 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17