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Publication | Closed Access

Noncanonical regulation of HOIL-1 on cancer stemness and sorafenib resistance identifies pixantrone as a novel therapeutic agent for HCC

DOI

10

Citations

30

References

2023

Year

Peng Chen, Zheyu Dong, Wei Zhu, Junling Chen, Yuxin Zhou, Qiuyue Ye, Xinxin Liao, Yongfa Tan, Chuanjiang Li, Yuhao Wang,
Hepatology

Abstract

HOIL-1 is critical in promoting sorafenib resistance and CSC properties of HCC through Notch1 signaling. Pixantrone targeting HOIL-1 restrains the sorafenib resistance and provides a potential therapeutic intervention for HCC.

References

YearCitations

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