Efficient regio- and stereo-selective C–H bond hydroxylation of steroids using an engineered heme-thiolate peroxygenase biocatalyst

Jinia Akter, Eva F. Hayball, Stephen G. Bell

Catalysis Science & Technology · 2023 · 12 citations · 16 references

Concepts

Abstract

A steroid hydroxylating monooxygenase enzyme was converted into a peroxygenase to enable the stereoselective hydroxylation of C–H bonds in these complex molecules simply by adding hydrogen peroxide.

References

16