Concepedia

Steroid Hydroxylation

Steroid Hydroxylation is a biochemical reaction in steroid catabolism wherein a hydroxyl group is enzymatically introduced into a steroid molecule, distinguishing it from other metabolic modifications by its site-specific oxidation mediated by cytochrome P450 enzymes.

807

Publications

33K

Citations

2.4K

Authors

651

Institutions

Publications per year

2017–2026

51

Parents

Publications

807

Utilization of Oxygen and Reduced Nicotinamide Adenine Dinucleotide Phosphate by Human Placental Microsomes during Aromatization of Androstenedione

E. Aubrey Thompson, Pentti K. Siiteri · Journal of Biological Chemistry · 1974 · 696 citations · Full text

, , +17

The Involvement of Human Placental Microsomal Cytochrome P-450 in Aromatization

E. Aubrey Thompson, Pentti K. Siiteri · Journal of Biological Chemistry · 1974 · 588 citations · Full text

, , +16

Regio- and stereoselectivity of P450-catalysed hydroxylation of steroids controlled by laboratory evolution

Sabrina Kille, Felipe E. Zilly, Juan Pablo Acevedo et al. · Nature Chemistry · 2011 · 413 citations

, , +13

Relation of steroid structure to enzyme induction in hepatoma tissue culture cells

Herbert H. Samuels, Gordon M. Tomkins · Journal of Molecular Biology · 1970 · 399 citations

, , +14

Regio- and stereoselective metabolism of two C19 steroids by five highly purified and reconstituted rat hepatic cytochrome P-450 isozymes.

Alexander W. Wood, Dene E. Ryan, Wayne Levin · Journal of Biological Chemistry · 1983 · 340 citations · Full text

, , +17

1–5 of 807

Authors

2.4K

  1. RB
    Rita Bernhardt

    Saarland University, Germany

    24 publications · 980 citations

    19

    h-index

  2. SB
    Seymour Bernstein

    University of Chicago, United States

    14 publications · 327 citations

    12

    h-index

  3. JG
    Jan-Ακε Gustafsson

    Karolinska Institutet, Sweden

    11 publications · 557 citations

    11

    h-index

  4. RI
    Ralph I. Dorfman

    Case Western Reserve University, United States

    11 publications · 757 citations

    11

    h-index

  5. MH
    Milton Heller

    American Chemical Society, United States

    9 publications · 232 citations

    9

    h-index

1–5 of 2.4K

Institutions

651

  1. Saarland University

    Saarbrücken, Germany

    18 h-index

    83 publications

    3.3K citations

  2. Karolinska Institutet

    Stockholm, Sweden

    18 h-index

    42 publications

    2.5K citations

  3. University of Edinburgh

    Edinburgh, United Kingdom

    13 h-index

    42 publications

    1.4K citations

  4. Columbia University

    New York, United States

    11 h-index

    28 publications

    2.5K citations

  5. Max Delbrück Center

    Berlin, Germany

    10 h-index

    35 publications

    1.4K citations

  6. Novartis (Switzerland)

    Basel, Switzerland

    9 h-index

    30 publications

    1K citations

  7. The University of Texas Southwestern Medical Center

    Dallas, United States

    9 h-index

    26 publications

    1.9K citations

  8. Analytisches Laboratorium

    Luhnstedt, Germany

    8 h-index

    36 publications

    1.5K citations

1–8 of 651

Venues

  1. Journal of Biological Chemistry

    JBC · 45 publications · 4.4K citations

    33

    h-index

  2. Journal of the American Chemical Society

    JACS · 52 publications · 1.9K citations

    26

    h-index

  3. Steroids

    44 publications · 1.3K citations

    21

    h-index

  4. Archives of Biochemistry and Biophysics

    ABB · 28 publications · 1.3K citations

    21

    h-index

  5. European Journal of Biochemistry

    EJB · 20 publications · 907 citations

    19

    h-index

1–5