Concepedia

Discovery of selective and potent USP22 inhibitors via structure-based virtual screening and bioassays exerting anti-tumor activity

Yue Zhang, Jiankun Song, Yuanzhang Zhou, Huijun Jia, Tianyu Zhou, Yingbo Sun, Qiong Gao, Yue Zhao, Yujie Pan, Zhaolin Sun,

Bioorganic Chemistry · 2023 · 15 citations · 29 references

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29

Open Babel: An open chemical toolbox

Noel M. O’Boyle, Michael Banck, Craig A. James et al. · Journal of Cheminformatics · 2011 · 11.1K citations · Full text

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Transcriptional activation via sequential histone H2B ubiquitylation and deubiquitylation, mediated by SAGA-associated Ubp8

Karl W. Henry, Anastasia Wyce, Wan‐Sheng Lo et al. · Genes & Development · 2003 · 701 citations · Full text

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How Molecular Size Impacts RMSD Applications in Molecular Dynamics Simulations

Karen Sargsyan, Cédric Grauffel, Carmay Lim · Journal of Chemical Theory and Computation · 2017 · 661 citations

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PD-L1 engagement on T cells promotes self-tolerance and suppression of neighboring macrophages and effector T cells in cancer

Brian Diskin, Salma Adam, Marcelo Ferreira Cassini et al. · Nature Immunology · 2020 · 397 citations

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USP22 Antagonizes p53 Transcriptional Activation by Deubiquitinating Sirt1 to Suppress Cell Apoptosis and Is Required for Mouse Embryonic Development

Zhenghong Lin, Hee‐Young Yang, Qingfei Kong et al. · Molecular Cell · 2012 · 317 citations · Full text

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