Concepedia

New thiazolidine-2,4-diones as effective anti-proliferative and anti-VEGFR-2 agents: Design, synthesis, in vitro, docking, MD simulations, DFT, ADMET, and toxicity studies

Hazem Elkady, Abdelrahman A. Abuelkhir, Mahmoud Rashed, Mohammed S. Taghour, Mohammed A. Dahab, Hazem A. Mahdy, Alaa Elwan, Hanan Al-Ghulikah, Eslam B. Elkaeed, Ibrahim M. Ibrahim,

Computational Biology and Chemistry · 2023 · 19 citations · 55 references

DOI

Concepts

References

55

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

Tim R. Mosmann · Journal of Immunological Methods · 1983 · 54.9K citations

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Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

Christopher A. Lipinski, Franco Lombardo, Beryl W. Dominy et al. · Advanced Drug Delivery Reviews · 1997 · 11K citations

, , +8

Essential dynamics of proteins

Andrea Amadei, Antonius B. M. Linssen, Herman J. C. Berendsen · Proteins Structure Function and Bioinformatics · 1993 · 3.4K citations

PLIP: fully automated protein–ligand interaction profiler

Sebastian Salentin, Sven B. Schreiber, V. Joachim Haupt et al. · Nucleic Acids Research · 2015 · 2.2K citations · Full text

Vascular Endothelial Growth Factor (VEGF) and Its Receptor (VEGFR) Signaling in Angiogenesis: A Crucial Target for Anti- and Pro-Angiogenic Therapies

Masaaki Shibuya · Genes & Cancer · 2011 · 1.7K citations

, , +24