Mahmoud Rashed

Design, synthesis, molecular modeling, in vivo studies and anticancer activity evaluation of new phthalazine derivatives as potential DNA intercalators and topoisomerase II inhibitors

Abdel‐Ghany A. El‐Helby, Helmy Sakr, Rezk R. Ayyad et al. · Bioorganic Chemistry · 2020 · 67 citations

Combinatorial Chemistry, Medicinal Chemistry, Derivative (Chemistry) +12

Novel fused imidazotriazines acting as promising top. II inhibitors and apoptotic inducers with greater selectivity against head and neck tumors: Design, synthesis, and biological assessments

Ahmed A. Al‐Karmalawy, Mahmoud Rashed, Marwa Sharaky et al. · European Journal of Medicinal Chemistry · 2023 · 26 citations · Full text

Medicinal Chemistry, Medicine, Ii Inhibitors +11

Ullmann reactions of 1-amino-4-bromoanthraquinones bearing various 2-substituents furnishing novel dyes

Enas M. Malik, Mahmoud Rashed, Lukas M. Wingen et al. · Dyes and Pigments · 2016 · 21 citations

Engineering, Organic Chemistry, Chemistry +5

New thiazolidine-2,4-diones as effective anti-proliferative and anti-VEGFR-2 agents: Design, synthesis, in vitro, docking, MD simulations, DFT, ADMET, and toxicity studies

Hazem Elkady, Abdelrahman A. Abuelkhir, Mahmoud Rashed et al. · Computational Biology and Chemistry · 2023 · 19 citations

Medicinal Chemistry, Pharmaceutical Science, Polymer-drug Conjugate +10

Identification of novel ureido benzothiophenes as dual VEGFR-2/EGFR anticancer agents

Wagdy M. Eldehna, Ghada H. Al-Ansary, Tarfah Al‐Warhi et al. · Bioorganic Chemistry · 2023 · 18 citations

Tumor Biology, Medicinal Chemistry, Urology +9