Concepedia

Mitochondrial vulnerability to oxidation in human brain organoids modelling Alzheimer's disease

Mariana Holubiec, Matías Alloatti, Julieta Bianchelli, Francisco Greloni, Cayetana Arnaiz, Melina Gonzalez Prinz, Iván Fernández Bessone, Victorio M. Pozo Devoto, Tomás L. Falzone

Free Radical Biology and Medicine · 2023 · 16 citations · 25 references

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25

Cerebral organoids model human brain development and microcephaly

Madeline A. Lancaster, Magdalena Renner, Carol-Anne Martin et al. · Nature · 2013 · 5.4K citations · Full text

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Impaired mitochondrial dynamics and abnormal interaction of amyloid beta with mitochondrial protein Drp1 in neurons from patients with Alzheimer's disease: implications for neuronal damage

Maria Mańczak, Marcus J. Calkins, P. Hemachandra Reddy · Human Molecular Genetics · 2011 · 813 citations · Full text

, , +17

Accumulation of Amyloid Precursor Protein in the Mitochondrial Import Channels of Human Alzheimer’s Disease Brain Is Associated with Mitochondrial Dysfunction

Latha Devi, Badanavalu M. Prabhu, Domenico F. Galati et al. · Journal of Neuroscience · 2006 · 787 citations · Full text

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Early deficits in synaptic mitochondria in an Alzheimer's disease mouse model

Heng Du, Lan Guo, Shiqiang Yan et al. · Proceedings of the National Academy of Sciences · 2010 · 705 citations · Full text

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A 3D human triculture system modeling neurodegeneration and neuroinflammation in Alzheimer’s disease

Joseph Park, Isaac Wetzel, Ian Marriott et al. · Nature Neuroscience · 2018 · 664 citations · Full text

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