A 3D human triculture system modeling neurodegeneration and neuroinflammation in Alzheimer’s disease

Joseph Park, Isaac Wetzel, Ian Marriott, +5

Nature Neuroscience

Neurodegenerative DiseasesAlzheimer's DiseaseComputational NeuroscienceMedicineHuman Triculture System +7

Cloning and functional expression of a rat kidney extracellular calcium/polyvalent cation-sensing receptor.

Daniela Riccardi, Joseph Park, W S Lee, +3

Proceedings of the National Academy of Sciences

Cellular PhysiologyMolecular PharmacologyRenal FunctionParathyroid HormoneRenal Pharmacology +17

Astrocytic interleukin-3 programs microglia and limits Alzheimer’s disease

Cameron S. McAlpine, Joseph Park, Ana Griciuc, +24

Nature

Neurodegenerative DiseasesAlzheimer's DiseaseLimits Alzheimer ’MedicineBrain-immune Interaction +5

Rqc2p and 60 <i>S</i> ribosomal subunits mediate mRNA-independent elongation of nascent chains

Peter Shen, Joseph Park, Yidan Qin, +9

Science

Epigenomic and transcriptomic analyses define core cell types, genes and targetable mechanisms for kidney disease

Hongbo Liu, Tomohito Doke, Dong Guo, +14

Nature Genetics

Renal FunctionFunctional GenomicsTranscriptomic AnalysesGeneticsMedicine +13

Rapid upregulation and clearance of distinct circulating microRNAs after prolonged aerobic exercise

Aaron L. Baggish, Joseph Park, Pil‐Ki Min, +9

Journal of Applied Physiology

Physical ActivityMuscle HypertrophyAerobic ExerciseConventional Protein BiomarkersKinesiology +19

Three-Dimensional Blood-Brain Barrier Model for in vitro Studies of Neurovascular Pathology

Hansang Cho, Ji Hae Seo, Keith H.K. Wong, +6

Scientific Reports

A multiancestry genome-wide association study of unexplained chronic ALT elevation as a proxy for nonalcoholic fatty liver disease with histological and radiological validation

Marijana Vujković, Shweta Ramdas, Kimberly Lorenz, +84

Nature Genetics

Genome-wide Association StudyMetabolic SyndromeMetabolic Associated SteatohepatitisHepatologyMetabolic Associated Steatotic Liver Disease +13

Infiltrating CD8+ T cells exacerbate Alzheimer’s disease pathology in a 3D human neuroimmune axis model

Mehdi Jorfi, Joseph Park, Clare K. Hall, +10

Nature Neuroscience

Neurodegenerative DiseasesAlzheimer's DiseaseMedicineImmunologyDisease Pathology +10

Consecutive Targetable Smart Nanoprobe for Molecular Recognition of Cytoplasmic microRNA in Metastatic Breast Cancer

Eunjung Kim, Jaemoon Yang, Joseph Park, +6

ACS Nano

Breast OncologyEngineeringSmart NanoprobeExtracellular MicrovesiclesBiomedical Engineering +17