Sonodynamic amplification of cGAS-STING activation by cobalt-based nanoagonist against bone and metastatic tumor

STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling

Hiroki Ishikawa, Glen N. Barber · Nature · 2008 · 3.4K citations · Full text

Inflammation, Host Response, Molecular Immunology +9

STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity

Hiroki Ishikawa, Zhe Ma, Glen N. Barber · Nature · 2009 · 2.6K citations · Full text

Inflammation, Host Response, Interferon-dependent Innate Immunity +7

STING-Dependent Cytosolic DNA Sensing Mediates Innate Immune Recognition of Immunogenic Tumors

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Cancer Immunosurveillance, Innate Immune System, Immunology +8

Direct Activation of STING in the Tumor Microenvironment Leads to Potent and Systemic Tumor Regression and Immunity

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Cytoplasmic chromatin triggers inflammation in senescence and cancer

Zhixun Dou, Kanad Ghosh, Maria Grazia Vizioli et al. · Nature · 2017 · 1.2K citations · Full text

Chromatin, Chromatin Remodeling, Medicine +5