Targeted heart repair by Tβ4-loaded cardiac-resident macrophage-derived extracellular vesicles modified with monocyte membranes

Embryonic and Adult-Derived Resident Cardiac Macrophages Are Maintained through Distinct Mechanisms at Steady State and during Inflammation

Slava Epelman, Kory J. Lavine, Anna E. Beaudin et al. · Immunity · 2014 · 1.4K citations · Full text

Life Sciences, Cell Biology, Immunology +12

Dynamic Biodistribution of Extracellular Vesicles <i>in Vivo</i> Using a Multimodal Imaging Reporter

Charles Pin‐Kuang Lai, Osama Mardini, Maria Ericsson et al. · ACS Nano · 2014 · 920 citations

Medicine, Biomedical Sciences, Pharmacokinetics +17

Self-renewing resident cardiac macrophages limit adverse remodeling following myocardial infarction

Sarah A. Dick, Jillian Macklin, Sara Nejat et al. · Nature Immunology · 2018 · 869 citations · Full text

Medicine, Cardiology, Immunology +13

Macrophages are required for neonatal heart regeneration

Arin B. Aurora, Enzo R. Porrello, Wei Tan et al. · Journal of Clinical Investigation · 2014 · 808 citations · Full text

Life Sciences, Cardiology, Immunology +17

Distinct macrophage lineages contribute to disparate patterns of cardiac recovery and remodeling in the neonatal and adult heart

Kory J. Lavine, Slava Epelman, Keita Uchida et al. · Proceedings of the National Academy of Sciences · 2014 · 801 citations · Full text

Life Sciences, Biology, Immunology +15