Targeting ferroptosis attenuates podocytes injury and delays tubulointerstitial fibrosis in focal segmental glomerulosclerosis

Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice

José Pedro Friedmann Angeli, Manuela Schneider, Bettina Proneth et al. · Nature Cell Biology · 2014 · 3.6K citations

Medicine, Nephrology, Pathobiology +10

A Conditionally Immortalized Human Podocyte Cell Line Demonstrating Nephrin and Podocin Expression

Moin A. Saleem, Michael J. O’Hare, Jochen Reiser et al. · Journal of the American Society of Nephrology · 2002 · 1.1K citations

Life Sciences, Cell Biology, Molecular Biology +16

Ginkgolide B alleviates oxidative stress and ferroptosis by inhibiting GPX4 ubiquitination to improve diabetic nephropathy

Jing Chen, Zhijie Ou, Tiantian Gao et al. · Biomedicine & Pharmacotherapy · 2022 · 176 citations · Full text

Medicine, Biochemistry, Pharmacology +17

Deficient Autophagy Results in Mitochondrial Dysfunction and FSGS

Takahisa Kawakami, Ivan G. Gomez, Shuyu Ren et al. · Journal of the American Society of Nephrology · 2014 · 174 citations · Full text

Medicine, Pathobiology, Pathology +17

Targeting Ferroptosis Attenuates Interstitial Inflammation and Kidney Fibrosis

Lu Zhou, Xian Xue, Qing Hou et al. · Kidney Diseases · 2021 · 106 citations · Full text

Medicine, Nephrology, Pathobiology +17