Concepedia

Optineurin tunes outside-in signaling to regulate lysosome biogenesis and phagocytic clearance in the retina

Li Xuan Tan, Colin J. Germer, Thushara Thamban, Nilsa La Cunza, Aparna Lakkaraju

Current Biology · 2023 · 23 citations · 68 references

DOIFull text

Open access

Concepts

References

68

Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2

Michael I. Love, Wolfgang Huber, Simon Anders · Genome biology · 2014 · 100.5K citations · Full text

, , +15

TFEB Links Autophagy to Lysosomal Biogenesis

Carmine Settembre, Chiara Di Malta, Vinicia Assunta Polito et al. · Science · 2011 · 3.3K citations

, , +17

Direct observation of individual endogenous protein complexes in situ by proximity ligation

Ola Söderberg, Mats Gullberg, Malin Jarvius et al. · Nature Methods · 2006 · 2.4K citations

, , +12

Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer’s disease

Evandro Fei Fang, Yujun Hou, Konstantinos Palikaras et al. · Nature Neuroscience · 2019 · 1.7K citations · Full text

, , +14

Lysosomal calcium signalling regulates autophagy through calcineurin and TFEB

Diego L. Medina, Simone Di Paola, Ivana Peluso et al. · Nature Cell Biology · 2015 · 1.4K citations

, , +12