Transcriptomics analysis and fed-batch regulation of high astaxanthin-producing <i>Phaffia rhodozyma</i>/<i>Xanthophyllomyces dendrorhous</i> obtained through adaptive laboratory evolution

Abstract

A high-yield astaxanthin strain (ALE105) was obtained through TiO2 domestication, and its metabolic mechanism was analysed by transcriptomics, which combined with nitrogen source regulation to further improve astaxanthin yield.