Highly-sensitive and homogenous detection of 8-oxoguanine based DNA oxidative damage by a CRISPR-enhanced structure-switching aptamer assay

Functional DNA Regulated CRISPR-Cas12a Sensors for Point-of-Care Diagnostics of Non-Nucleic-Acid Targets

Ying Xiong, Ying Xiong, Jingjing Zhang et al. · Journal of the American Chemical Society · 2019 · 671 citations · Full text

Engineering, Biotechnology, Molecular Biology +17

The importance of DNA repair for maintaining oocyte quality in response to anti-cancer treatments, environmental toxins and maternal ageing

Amy Winship, Jessica M. Stringer, Seng H. Liew et al. · Human Reproduction Update · 2018 · 159 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Toward consensus in the analysis of urinary 8‐oxo‐7,8‐dihydro‐2′‐deoxyguanosine as a noninvasive biomarker of oxidative stress

Mark D. Evans, Ryszard Oliński, Steffen Loft et al. · The FASEB Journal · 2009 · 143 citations · Full text

Pharmacy, Biochemistry, Analytical Toxicology +15

CRISPR-Cas12a based aptasensor for sensitive and selective ATP detection

Lei Peng, Jin Zhou, Guozhen Liu et al. · Sensors and Actuators B Chemical · 2020 · 128 citations

Engineering, Biotechnology, Molecular Biology +11

Female ageing affects the DNA repair capacity of oocytes in IVF using a controlled model of sperm DNA damage in mice

Fabrizzio Horta, Sally Catt, Prakash Ramachandran et al. · Human Reproduction · 2019 · 108 citations · Full text

Life Sciences, Genetics, Molecular Biology +15