Concepedia

Gut microbiome and reproductive endocrine diseases: a Mendelian randomization study

Ye Liang, Weihong Zeng, Tao Hou, Haikun Yang, Boming Wu, Ru Pan, Lishan Huang

Frontiers in Endocrinology · 2023 · 28 citations · 61 references

DOIFull text

Open access

Abstract

Our study provides evidence that gut microbiome is closely related with REDs. Subsequent studies should be conducted to promote microbiome-orientated therapeutic strategies for managing REDs.

References

61

Mendelian randomization with invalid instruments: effect estimation and bias detection through Egger regression

Jack Bowden, George Davey Smith, Stephen Burgess · International Journal of Epidemiology · 2015 · 10.2K citations · Full text

Consistent Estimation in Mendelian Randomization with Some Invalid Instruments Using a Weighted Median Estimator

Jack Bowden, George Davey Smith, Philip Haycock et al. · Genetic Epidemiology · 2016 · 9.2K citations · Full text

Detection of widespread horizontal pleiotropy in causal relationships inferred from Mendelian randomization between complex traits and diseases

Marie Verbanck, Chia‐Yen Chen, Benjamin M. Neale et al. · Nature Genetics · 2018 · 8.8K citations · Full text

, , +13

Mendelian Randomization Analysis With Multiple Genetic Variants Using Summarized Data

Stephen Burgess, Adam S. Butterworth, Simon G. Thompson · Genetic Epidemiology · 2013 · 6.2K citations · Full text

, , +28

Interpreting findings from Mendelian randomization using the MR-Egger method

Stephen Burgess, Simon G. Thompson · European Journal of Epidemiology · 2017 · 4.6K citations · Full text