Concepedia

Genomic alterations involved in fluoroquinolone resistance development in Staphylococcus aureus

Thuc Quyen Huynh, Van Nhi Tran, Van Chi Thai, Hoang An Nguyen, Ngoc Thuy Giang Nguyen, Minh Khang Tran, Thi Phuong Truc Nguyen, Cat Anh Le, L. Ho, Navenaah Udaya Surian,

PLoS ONE · 2023 · 22 citations · 59 references

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Open access

Abstract

The emergence of MDR S. aureus was associated with the mutations in the FQ-target sequences and the overexpression of efflux pump systems and their regulators.

References

59

Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes

Marilyn Kozak · Cell · 1986 · 4.8K citations

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Upstream open reading frames cause widespread reduction of protein expression and are polymorphic among humans

Sarah E. Calvo, David J. Pagliarini, Vamsi K. Mootha · Proceedings of the National Academy of Sciences · 2009 · 922 citations · Full text

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Sequence signatures and mRNA concentration can explain two‐thirds of protein abundance variation in a human cell line

Christine Vogel, Raquel de Sousa Abreu, Daijin Ko et al. · Molecular Systems Biology · 2010 · 624 citations · Full text

mRNA structure regulates protein expression through changes in functional half-life

David Mauger, B. Joseph Cabral, Vladimir Presnyak et al. · Proceedings of the National Academy of Sciences · 2019 · 529 citations · Full text

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Multidrug Efflux Pumps in Staphylococcus aureus: an Update

Sofia Santos Costa, Miguel Viveiros, Leonard Amaral et al. · The Open Microbiology Journal · 2013 · 394 citations · Full text