Concepedia

Human umbilical cord-derived mesenchymal stromal cells alleviate liver cirrhosis through the Hippo/YAP/Id1 pathway and macrophage-dependent mechanism

Lichao Yao, Xue Hu, Mengqin Yuan, Pingji Liu, Qiuling Zhang, Zheng Wang, Ping Chen, Zhiyu Xiong, Lun Wu, Kai Dai,

International Immunopharmacology · 2023 · 13 citations · 23 references

DOI

Concepts

References

23

TLR4 enhances TGF-β signaling and hepatic fibrosis

Ekihiro Seki, Samuele De Minicis, Christoph H. Österreicher et al. · Nature Medicine · 2007 · 1.9K citations

, , +14

Liver cirrhosis

The Lancet · 2021 · 1.5K citations

, , +13

Fate tracing reveals hepatic stellate cells as dominant contributors to liver fibrosis independent of its aetiology

Ingmar Mederacke, Christine Hsu, Juliane S. Troeger et al. · Nature Communications · 2013 · 1.4K citations · Full text

, , +12

Mechanical strain induces E-cadherin–dependent Yap1 and β-catenin activation to drive cell cycle entry

Blair W. Benham-Pyle, Beth L. Pruitt, W. James Nelson · Science · 2015 · 557 citations · Full text

, , +16

The Hippo pathway effector YAP controls mouse hepatic stellate cell activation

Inge Mannaerts, Sofia Batista Leite, Stefaan Verhulst et al. · Journal of Hepatology · 2015 · 390 citations

, , +12