The million-molecule challenge: a moonshot project to rapidly advance longevity intervention discovery

Rapamycin fed late in life extends lifespan in genetically heterogeneous mice

Randy Strong, Z. Dave Sharp, James F. Nelson et al. · Nature · 2009 · 3.7K citations · Full text

Education, Genetics, Nutrition +15

A C. elegans mutant that lives twice as long as wild type

Cynthia Kenyon, Jean Chang, Erin Gensch et al. · Nature · 1993 · 3.4K citations

Life Sciences, Biology, Genetics +6

Geroscience: Linking Aging to Chronic Disease

Brian K. Kennedy, Shelley L. Berger, Anne Brunet et al. · Cell · 2014 · 2.7K citations · Full text

Education, Geriatric Medicine, Aging +11

The Effect of Retarded Growth Upon the Length of Life Span and Upon the Ultimate Body Size

C. M. McCay, Mary F. Crowell, L. A. Maynard · Journal of Nutrition · 1935 · 2.3K citations

Education, Developmental Biology, Human Development +14

Regulation of Yeast Replicative Life Span by TOR and Sch9 in Response to Nutrients

Matt Kaeberlein, Ryan Powers, Kristan K. Steffen et al. · Science · 2005 · 1.3K citations

Life Sciences, Genetics, Molecular Genetics +17