Concepedia

Single-cell RNA sequencing identifies critical transcription factors of tumor cell invasion induced by hypoxia microenvironment in glioblastoma

Yanru Zhang, Bo Zhang, Chengqian Lv, Nan Zhang, Kaiyuan Xing, Zixuan Wang, Rongkai Lv, Mingchen Yu, Chaohan Xu, Yihan Wang

Theranostics · 2023 · 36 citations · 49 references

DOIFull text

Open access

Concepts

Abstract

Our work revealed the critical regulators in hypoxic subpopulation with high invasive potential in GBM, which may have practical implications for clinical targeted-hypoxia cancer drug therapy.

References

49

clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters

Guangchuang Yu, Li-Gen Wang, Yanyan Han et al. · OMICS A Journal of Integrative Biology · 2012 · 38.3K citations

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GSVA: gene set variation analysis for microarray and RNA-Seq data

Sonja Hänzelmann, Robert Castelo, Justin Guinney · BMC Bioinformatics · 2013 · 16.5K citations · Full text

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Integrating single-cell transcriptomic data across different conditions, technologies, and species

Andrew Butler, Paul Hoffman, Peter Smibert et al. · Nature Biotechnology · 2018 · 14.7K citations · Full text

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CBTRUS Statistical Report: Primary Brain and Central Nervous System Tumors Diagnosed in the United States in 2006-2010

Quinn T. Ostrom, Haley Gittleman, P Farah et al. · Neuro-Oncology · 2013 · 12.1K citations · Full text

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Inference and analysis of cell-cell communication using CellChat

Suoqin Jin, Christian F. Guerrero‐Juarez, Lihua Zhang et al. · Nature Communications · 2021 · 8.3K citations · Full text

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