Concepedia

Sulforaphane protects microvascular endothelial cells in lower limb ischemia/reperfusion injury mice

Fan‐Feng Chen, Jiayu Zhan, Abdullah Al Mamun, Yibing Tao, Shanshan Huang, Jiaxin Zhao, Yu Zhang, Yitie Xu, Shenghu Du, Wei Lü,

Food & Function · 2023 · 11 citations · 38 references

DOI

Concepts

Abstract

Mechanism by which SFN improving microvascular damage in limbs insulted by I/R injury. SFN activates TFEB via MCOLN1-calcineurin signaling. SFN-induced TFEB activation augments autophagy restoration, anti-oxidant response and anti-apoptosis effect.

References

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, , +17