Concepedia

Miniaturization of popular reactions from the medicinal chemists’ toolbox for ultrahigh-throughput experimentation

Nathan J. Gesmundo, Kevin D. Dykstra, James L. Douthwaite, Yu-Ting Kao, Ruheng Zhao, Babak Mahjour, Ron L. Ferguson, Spencer D. Dreher, Bérengère Sauvagnat, Josep Saurí,

Nature Synthesis · 2023 · 41 citations · 31 references

DOI

Concepts

References

31

The Medicinal Chemist’s Toolbox: An Analysis of Reactions Used in the Pursuit of Drug Candidates

Stephen D. Roughley, Allan M. Jordan · Journal of Medicinal Chemistry · 2011 · 2.7K citations

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Analysis of Past and Present Synthetic Methodologies on Medicinal Chemistry: Where Have All the New Reactions Gone?

Dean G. Brown, Jonas Boström · Journal of Medicinal Chemistry · 2015 · 2K citations · Full text

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Reductive Amination of Aldehydes and Ketones with Sodium Triacetoxyborohydride. Studies on Direct and Indirect Reductive Amination Procedures<sup>1</sup>

Ahmed F. Abdel‐Magid, Kenneth G. Carson, Bruce D. Harris et al. · The Journal of Organic Chemistry · 1996 · 1.5K citations

, , +10

Updating and further expanding GSK's solvent sustainability guide

Catherine M. Alder, John Hayler, Richard K. Henderson et al. · Green Chemistry · 2016 · 1K citations

, , +7

Nanomole-scale high-throughput chemistry for the synthesis of complex molecules

A. Buitrago Santanilla, Erik L. Regalado, Tony Pereira et al. · Science · 2014 · 649 citations

, , +13