Concepedia

High-throughput Reaction Optimization

High-Throughput Reaction Optimization is a systematic methodology within high-throughput synthesis that enables the rapid and parallelized evaluation of multiple reaction parameters to identify optimal conditions for chemical transformations with enhanced efficiency and precision.

168

Publications

8.9K

Citations

824

Authors

240

Institutions

Publications per year

2017–2026

86

Parents

Publications

168

Nanomole-scale high-throughput chemistry for the synthesis of complex molecules

A. Buitrago Santanilla, Erik L. Regalado, Tony Pereira et al. · Science · 2014 · 649 citations

, , +13

Reconfigurable system for automated optimization of diverse chemical reactions

Anne‐Catherine Bédard, Andrea Adamo, Kosi C. Aroh et al. · Science · 2018 · 499 citations · Full text

, , +17

Automated self-optimization, intensification, and scale-up of photocatalysis in flow

Aidan Slattery, Zhenghui Wen, Pauline Tenblad et al. · Science · 2024 · 284 citations · Full text

, , +17

High-Throughput Optimization of Ir-Catalyzed C–H Borylation: A Tutorial for Practical Applications

Sean Preshlock, Behnaz Ghaffari, Peter E. Maligres et al. · Journal of the American Chemical Society · 2013 · 221 citations

, , +17

Nickel-Catalyzed Asymmetric Alkene Hydrogenation of α,β-Unsaturated Esters: High-Throughput Experimentation-Enabled Reaction Discovery, Optimization, and Mechanistic Elucidation

Michael Shevlin, Max R. Friedfeld, Huaming Sheng et al. · Journal of the American Chemical Society · 2016 · 211 citations · Full text

, , +16

1–5 of 168

Authors

824

  1. JD
    Jason D. Williams

    University of Graz, Austria

    4 publications · 119 citations

    4

    h-index

  2. TC
    Tim Cernak

    University of Michigan, United States

    4 publications · 769 citations

    4

    h-index

  3. CO
    C. Oliver Kappe

    University of Graz, Austria

    4 publications · 121 citations

    4

    h-index

  4. KF
    Klavs F. Jensen

    Massachusetts Institute of Technology, United States

    4 publications · 896 citations

    4

    h-index

  5. MS
    Michael Shevlin

    Merck & Co., Inc., Rahway, NJ, USA (United States), United States

    3 publications · 910 citations

    3

    h-index

1–5 of 824

Institutions

240

  1. Merck & Co., Inc., Rahway, NJ, USA (United States)

    Rahway, United States

    12 h-index

    70 publications

    14.3K citations

  2. Centre National de la Recherche Scientifique

    Paris, France

    9 h-index

    46 publications

    3.4K citations

  3. Pfizer (United States)

    New York, United States

    6 h-index

    51 publications

    1.8K citations

  4. Massachusetts Institute of Technology

    Cambridge, United States

    6 h-index

    29 publications

    5.7K citations

  5. University of California, Los Angeles

    Los Angeles, United States

    5 h-index

    13 publications

    579 citations

  6. GlaxoSmithKline (United Kingdom)

    London, United Kingdom

    4 h-index

    11 publications

    507 citations

  7. Princeton University

    Princeton, United States

    4 h-index

    15 publications

    1.8K citations

  8. University of Graz

    Graz, Austria

    4 h-index

    13 publications

    400 citations

1–8 of 240

Venues

  1. Organic Process Research & Development

    37 publications · 1.6K citations

    24

    h-index

  2. Angewandte Chemie International Edition

    7 publications · 481 citations

    8

    h-index

  3. Organic Letters

    OL · 6 publications · 410 citations

    6

    h-index

  4. The Journal of Organic Chemistry

    JOC · 6 publications · 275 citations

    6

    h-index

  5. Chemistry - A European Journal

    5 publications · 417 citations

    5

    h-index

1–5