Concepedia

MCL1 regulates AML cells metabolism via direct interaction with HK2. Metabolic signature at onset predicts overall survival in AMLs’ patients

Gianfranco Catalano, Alessandra Zaza, Cristina Banella, Elvira Pelosi, Germana Castelli, Elisabetta De Marinis, Ariela Smigliani, Serena Travaglini, Tiziana Ottone, Mariadomenica Divona,

Leukemia · 2023 · 27 citations · 33 references

DOIFull text

Open access

Concepts

References

33

BCL-2 Inhibition Targets Oxidative Phosphorylation and Selectively Eradicates Quiescent Human Leukemia Stem Cells

Eleni D. Lagadinou, Alexander Sach, Kevin P. Callahan et al. · Cell stem cell · 2013 · 1.4K citations · Full text

, , +12

Mechanisms of apoptosis sensitivity and resistance to the BH3 mimetic ABT-737 in acute myeloid leukemia

Marina Konopleva, Rooha Contractor, Twee Tsao et al. · Cancer Cell · 2006 · 1K citations · Full text

, , +16

Mitochondrial Binding of Hexokinase II Inhibits Bax-induced Cytochrome c Release and Apoptosis

John G. Pastorino, Nataly Shulga, Jan B. Hoek · Journal of Biological Chemistry · 2002 · 697 citations · Full text

, , +17

MYC and MCL1 Cooperatively Promote Chemotherapy-Resistant Breast Cancer Stem Cells via Regulation of Mitochondrial Oxidative Phosphorylation

Kyung‐min Lee, Jennifer M. Giltnane, Justin M. Balko et al. · Cell Metabolism · 2017 · 646 citations · Full text

, , +12

Tracing the origins of relapse in acute myeloid leukaemia to stem cells

Liran I. Shlush, Amanda Mitchell, Lawrence E. Heisler et al. · Nature · 2017 · 582 citations

, , +12