Matrix stiffness regulates the tight junction phenotypes and local barrier properties in tricellular regions in an iPSC-derived BBB model

Chemically defined conditions for human iPSC derivation and culture

Guokai Chen, Daniel R. Gulbranson, Zhonggang Hou et al. · Nature Methods · 2011 · 1.5K citations · Full text

Life Sciences, Biochemistry, Biotechnology +8

Derivation of blood-brain barrier endothelial cells from human pluripotent stem cells

Ethan S. Lippmann, Samira M. Azarin, Jennifer E. Kay et al. · Nature Biotechnology · 2012 · 828 citations · Full text

Life Sciences, Cell Biology, Neuroscience +14

Tricellulin constitutes a novel barrier at tricellular contacts of epithelial cells

Junichi Ikenouchi, Mikio Furuse, Kyoko Furuse et al. · The Journal of Cell Biology · 2005 · 768 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

A retinoic acid-enhanced, multicellular human blood-brain barrier model derived from stem cell sources

Ethan S. Lippmann, Abraham Al‐Ahmad, Samira M. Azarin et al. · Scientific Reports · 2014 · 520 citations · Full text

Life Sciences, Cell Biology, Neuroscience +16

Cell-Cycle Control by Physiological Matrix Elasticity and In Vivo Tissue Stiffening

Eric A. Klein, Liqun Yin, Devashish Kothapalli et al. · Current Biology · 2009 · 426 citations · Full text

Natural Sciences, Biophysics, Cell Biology +16