Discovery of intracellular self-assembly protein degraders driven by tumor-specific activatable bioorthogonal reaction

Intratumoral Copper Modulates PD-L1 Expression and Influences Tumor Immune Evasion

Florida Voli, Emanuele Valli, Luigi Lerra et al. · Cancer Research · 2020 · 419 citations · Full text

Medicine, Immunology, Oncology +17

Protein Degradation by In-Cell Self-Assembly of Proteolysis Targeting Chimeras

Honorine Lebraud, David J. Wright, Christopher N. Johnson et al. · ACS Central Science · 2016 · 396 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Copper and Zinc levels in normal and malignant tissues

Ehud J. Margalioth, Joseph G. Schenker, Mordechai Chevion · Cancer · 1983 · 300 citations · Full text

Medicine, Oncology, Pathology +6

Cancer Selective Target Degradation by Folate-Caged PROTACs

Jing Liu, He Chen, Yi Liu et al. · Journal of the American Chemical Society · 2021 · 288 citations · Full text

Pharmacy, Oncology, Pharmacology +15

Epigenetic regulation of ferroptosis via ETS1/miR-23a-3p/ACSL4 axis mediates sorafenib resistance in human hepatocellular carcinoma

Yuanjun Lu, Yau-Tuen Chan, Hor‐Yue Tan et al. · Journal of Experimental & Clinical Cancer Research · 2022 · 213 citations · Full text

Life Sciences, Molecular Biology, Oncology +17