Production and characterization of a camelid single domain anti-CD22 antibody conjugated to DM1

Synthesis of site-specific antibody-drug conjugates using unnatural amino acids

Jun Y. Axup, Krishna Bajjuri, Melissa Ritland et al. · Proceedings of the National Academy of Sciences · 2012 · 582 citations · Full text

Pharmacy, Medicinal Chemistry, Oncology +17

Antibody-Drug Conjugates for the Treatment of Non–Hodgkin's Lymphoma: Target and Linker-Drug Selection

Andrew G. Polson, Jill Calemine-Fenaux, Pamela Chan et al. · Cancer Research · 2009 · 249 citations

Medicine, Oncology, Pharmacology +17

Statistical Modeling of the Drug Load Distribution on Trastuzumab Emtansine (Kadcyla), a Lysine-Linked Antibody Drug Conjugate

Michael T. Kim, Yan Chen, Joseph C. Marhoul et al. · Bioconjugate Chemistry · 2014 · 145 citations

Pharmacy, Pharmaceutics, Pharmacology +15

In-depth structural characterization of Kadcyla® (ado-trastuzumab emtansine) and its biosimilar candidate

Liuxi Chen, Lan Wang, Henry Shion et al. · mAbs · 2016 · 121 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmaceutics +17

Effect of Dye and Conjugation Chemistry on the Biodistribution Profile of Near-Infrared-Labeled Nanobodies as Tracers for Image-Guided Surgery

Pieterjan Debie, Jannah Van Quathem, Inge Hansen et al. · Molecular Pharmaceutics · 2017 · 103 citations

Medicine, Oncology, Pharmaceutics +17