Concepedia

Tripterygium glycosides reverse chemotherapy resistance in ovarian cancer by targeting the NRF2/GPX4 signal axis to induce ferroptosis of drug-resistant human epithelial ovarian cancer cells

Bo Ma, Yanying Zhong, Runqiu Chen, Xinlu Zhan, Genhua Huang, Yifei Xiong, Buzhen Tan

Biochemical and Biophysical Research Communications · 2023 · 16 citations · 14 references

DOI

Concepts

References

14

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

Scott J. Dixon, Kathryn M. Lemberg, Michael R. Lamprecht et al. · Cell · 2012 · 17K citations · Full text

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Regulation of Ferroptotic Cancer Cell Death by GPX4

Wan Seok Yang, Rohitha Sriramaratnam, Matthew Welsch et al. · Cell · 2014 · 7.1K citations · Full text

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The cytoprotective role of the Keap1–Nrf2 pathway

Liam Baird, Albena T. Dinkova‐Kostova · Archives of Toxicology · 2011 · 1K citations

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Nrf2 Enhances Cell Proliferation and Resistance to Anticancer Drugs in Human Lung Cancer

Shinsuke Homma, Yukio Ishii, Yuko Morishima et al. · Clinical Cancer Research · 2009 · 416 citations

Mitochondrial oxidative stress mediated Fe-induced ferroptosis via the NRF2-ARE pathway

Guang‐Hui Chen, Chang-Chun Song, Kostas Pantopoulos et al. · Free Radical Biology and Medicine · 2022 · 315 citations

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