CTSS Modulates Stress-Related Carotid Artery Thrombosis in a Mouse FeCl ₃ Model

Abstract

CTSS inhibition appeared to improve the stress-related thrombosis in mice that underwent FeCl₃-induction surgery, possibly by reducing vascular inflammation, oxidative stress, and apoptosis. CTSS could thus become a candidate therapeutic target for chronic psychological stress-related thrombotic events in metabolic cardiovascular disease.