Inflachromene attenuates seizure severity in mouse epilepsy models via inhibiting HMGB1 translocation

Toll-like receptor 4 and high-mobility group box-1 are involved in ictogenesis and can be targeted to reduce seizures

Mattia Maroso, Silvia Balosso, Teresa Ravizza et al. · Nature Medicine · 2010 · 901 citations · Full text

Synaptic Signaling, Medicine, Toll-like Receptor 4 +9

A revised Racine's scale for PTZ-induced seizures in rats

Annika Lüttjohann, Paolo Francesco Fabene, Gilles van Luijtelaar · Physiology & Behavior · 2009 · 383 citations

Revised Racine, Neurophysiology, Neuroanatomy +8

Interactions of pentamethylenetetrazole and tetrazole analogues with the picrotoxinin site of the benzodiazepine-gaba receptor-ionophore complex

R. Ramanjaneyulu, Maharaj K. Ticku · European Journal of Pharmacology · 1984 · 294 citations

Tetrazole Analogues, Picrotoxinin Site, Biochemistry +8

Interleukin-1 type 1 receptor/Toll-like receptor signalling in epilepsy: the importance of IL-1beta and high-mobility group box 1

Mattia Maroso, Silvia Balosso, Teresa Ravizza et al. · Journal of Internal Medicine · 2011 · 177 citations

Depolarized GABAergic Signaling in Subicular Microcircuits Mediates Generalized Seizure in Temporal Lobe Epilepsy

Yi Wang, Cenglin Xu, Zhenghao Xu et al. · Neuron · 2017 · 155 citations · Full text

Synaptic Plasticity, Neurophysiology, Depolarized Gabaergic Signaling +9