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Toll-like receptor 4 and high-mobility group box-1 are involved in ictogenesis and can be targeted to reduce seizures

Mattia Maroso, Silvia Balosso, Teresa Ravizza, Jaron Liu, Eleonora Aronica, Anand M. Iyer, Carlo Rossetti, Monica Molteni, Maura Casalgrandi, Angelo A. Manfredi,

Nature Medicine · 2010 · 912 citations · 45 references

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45

Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in <i>Tlr4</i> Gene

Alexander Poltorak, Xiaolong He, Irina Smirnova et al. · Science · 1998 · 7.6K citations

, , +17

Release of chromatin protein HMGB1 by necrotic cells triggers inflammation

Paola Scaffidi, Tom Misteli, Marco E. Bianchi · Nature · 2002 · 4.2K citations

, , +14

Toll-like receptor 4–dependent contribution of the immune system to anticancer chemotherapy and radiotherapy

Lionel Apétoh, François Ghiringhelli, Antoine Tesnière et al. · Nature Medicine · 2007 · 3K citations

, , +16

Incidence of Epilepsy and Unprovoked Seizures in Rochester, Minnesota: 1935–1984

W. Allen Hauser, John F. Annegers, Leonard T. Kurland · Epilepsia · 1993 · 2.1K citations

, , +8

Mediation of Poly(ADP-Ribose) Polymerase-1-Dependent Cell Death by Apoptosis-Inducing Factor

Seong-Woon Yu, Hongmin Wang, Marc F. Poitras et al. · Science · 2002 · 1.8K citations

, , +15