Jumonji domain‐containing protein‐3 (JMJD3) promotes myeloid fibroblast activation and macrophage polarization in kidney fibrosis

Abstract

Our study identifies JMJD3 as a critical regulator of myeloid fibroblast activation, macrophage polarization, and renal fibrosis development. Therefore, JMJD3 may represent a promising therapeutic target for chronic kidney disease.