Concepedia

ALOX5 promotes autophagy-dependent ferroptosis by activating the AMPK/mTOR pathway in melanoma

Min Wang, Guang Zeng, Bingrui Xiong, Xiaobin Zhu, Jia Guo, Lin Cai

Biochemical Pharmacology · 2023 · 78 citations · 17 references

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17

Cancer statistics, 2022

Rebecca L. Siegel, Kimberly D. Miller, Hannah E. Fuchs et al. · CA A Cancer Journal for Clinicians · 2022 · 18.2K citations · Full text

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Peroxidation of polyunsaturated fatty acids by lipoxygenases drives ferroptosis

Wan Seok Yang, Katherine J. Kim, Michael M. Gaschler et al. · Proceedings of the National Academy of Sciences · 2016 · 2.3K citations · Full text

, , +17

Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway

Vasanthi S. Viswanathan, Matthew J. Ryan, Harshil Dhruv et al. · Nature · 2017 · 2K citations · Full text

, , +16

Energy-stress-mediated AMPK activation inhibits ferroptosis

Hyemin Lee, Fereshteh Zandkarimi, Yilei Zhang et al. · Nature Cell Biology · 2020 · 1.1K citations · Full text

, , +7

Lymph protects metastasizing melanoma cells from ferroptosis

Jessalyn M. Ubellacker, Alpaslan Tasdogan, Vijayashree Ramesh et al. · Nature · 2020 · 924 citations · Full text

, , +12