Concepedia

Age of onset defines two distinct profiles of atopic dermatitis in adults

Paola Facheris, Joel Corrêa da Rosa, Angel D. Pagan, Michael Angelov, Ester Del Duca, Grace Rabinowitz, Pedro Jesús Gómez‐Arias, Camille Rothenberg‐Lausell, Yeriel Estrada, Swaroop Bose,

Allergy · 2023 · 39 citations · 49 references

DOI

Abstract

Age-of-onset delineates two distinct endophenotypes in adult AD potentially suggesting the need for broader (beyond Th2) therapeutic targeting in AOAD.

References

49

Linear Models and Empirical Bayes Methods for Assessing Differential Expression in Microarray Experiments

Gordon K. Smyth · Statistical Applications in Genetics and Molecular Biology · 2004 · 11.9K citations

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Homogenous 96-Plex PEA Immunoassay Exhibiting High Sensitivity, Specificity, and Excellent Scalability

Erika Assarsson, Martin Lundberg, Göran Holmquist et al. · PLoS ONE · 2014 · 1.8K citations · Full text

, , +27

Progressive activation of TH2/TH22 cytokines and selective epidermal proteins characterizes acute and chronic atopic dermatitis

Julia Gittler, Avner Shemer, Mayte Suárez‐Fariñas et al. · Journal of Allergy and Clinical Immunology · 2012 · 931 citations

, , +7

Dupilumab progressively improves systemic and cutaneous abnormalities in patients with atopic dermatitis

Emma Guttman‐Yassky, Robert Bissonnette, Benjamin Ungar et al. · Journal of Allergy and Clinical Immunology · 2018 · 647 citations

Dupilumab improves the molecular signature in skin of patients with moderate-to-severe atopic dermatitis

Jennifer D. Hamilton, Mayte Suárez‐Fariñas, Nikhil Dhingra et al. · Journal of Allergy and Clinical Immunology · 2014 · 460 citations · Full text